An Informative Guide to Ketamine Therapy: Efficacy, Safety, and Legality

All questions about ketamine therapy answered.

Ketamine therapy has emerged as a promising treatment for various chronic conditions, particularly in the management of severe depression, chronic pain, and certain psychiatric disorders. However, with its rise in popularity, many questions have arisen concerning its effects, costs, legal status, and safety. This article aims to address these concerns, providing valuable information for patients considering ketamine therapy at facilities like Florida Regional Pain Management in Jacksonville, Florida.

Does Ketamine Therapy Get You High?

Ketamine is a dissociative anesthetic that can cause altered perception, cognition, and mood, which some might describe as a ‘high.’ Hence the DEA classification as a potential drug of abuse. In medical settings, ketamine is administered in controlled, low doses, which minimizes psychoactive effects while leveraging its therapeutic properties. It’s crucial for patients to be aware that while some may experience mild euphoria during treatment, the purpose of medical ketamine therapy is not to induce a high but to target specific health issues.

Who is Not a Good Candidate for Ketamine Therapy?

Ketamine therapy is not suitable for everyone. Individuals with the following conditions or circumstances might be advised against this treatment:

  • Uncontrolled high blood pressure.
  • Active substance abuse issues.
  • Certain psychiatric conditions like psychosis.
  • Severe liver or heart disease.
  • Those with a history of ketamine allergy.

Consultation with a healthcare provider is essential to determine if ketamine therapy is appropriate based on your medical history and current health status.

How Much Does Ketamine Therapy Cost?

The cost of ketamine therapy can vary widely depending on the medical facility, geographical location, and the number of treatment sessions required. Typically, each session can range from $400 to $800, and a full course of treatment involves multiple sessions. At Florida Regional Pain Management, we offer a package discount for six treatments at $1,999 and maintenance treatments at $250.

Is Ketamine Therapy Covered by Insurance?

Currently, ketamine therapy is not covered by insurance as it is still considered an off-label treatment, especially for conditions like depression and CRPS. However, coverage can vary, and some insurance plans might cover ketamine therapy for approved indications such as anesthesia. Patients should check with their insurance providers to understand the specifics of their coverage.

Is Ketamine Therapy Legal?

Ketamine therapy is legal in the United States when administered by a licensed healthcare professional in a medical setting. While ketamine is classified as a Schedule III controlled substance due to its potential for abuse, its use in medicine is regulated and permitted under controlled circumstances.

Is Ketamine Therapy Safe?

When administered under the supervision of qualified medical professionals, ketamine therapy is generally safe. However, it is crucial to undergo treatment in a reputable medical facility that adheres to stringent protocols. Potential risks include dissociative effects, elevated blood pressure, and rare allergic reactions, which can be effectively managed in a controlled medical environment. Administration of doses beyond the guidelines may result in the administration of general anesthetic with the potential for the loss of airway and aspiration pneumonitis.


Ketamine therapy offers significant benefits for certain conditions, particularly where traditional treatments have failed. Understanding the nuances of this treatment, from its psychoactive effects to its legal status and safety profile, is crucial for those considering it as an option. At Florida Regional Pain Management, we are committed to providing our patients with safe, effective, and legally compliant treatment options tailored to their health needs. Dr. Manohar is a board-certified anesthesiologist, trained in administering intravenous anesthetics including intravenous ketamine. You can book your ketamine therapy session with Dr. Manohar here.  Alternatively you can call us at (904) 737-7246.

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